General description
FASTK is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis.
Immunogen
FASTK (NP_006703, 214-248)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human FASTK.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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